Design and Analysis of Long-Stroke Planar Switched Reluctance Motor for Positioning Applications

This paper presents the design, control, and experimental performance evaluation of a long-stroke planar switched reluctance motor (PSRM) for positioning applications. Based on comprehensive consideration of the electromagnetic and mechanical characteristics of the PSRM, a motor design is first developed to reduce the force ripple and deformation. A control scheme with LuGre friction compensation is then proposed to improve the positioning accuracy of the PSRM. Furthermore, this control scheme is proven to ensure the stable motion of the PSRM system. Additionally, the response speed and steady-state error of the PSRM system with this control scheme are theoretically analyzed. Finally, the experimental results are presented and analyzed. The effectiveness of the precision long-stroke motion of the PSRM and its promise for use in precision positioning applications are verified experimentally

Clinicopathological characteristics of gastrointestinal schwannomas: A retrospective analysis of 78 cases

IntroductionSchwannomas are tumors arising from Schwan cells of the neural sheath, which rarely occur in the gastrointestinal tract. The aim of the present study was to analyze the clinicopathological features and treatment outcomes of gastrointestinal schwannomas (GISs).MethodsPatients who were diagnosed with GISs in our hospital from January 2010 to December 2021 were selected. Data about demographic characteristics, clinical symptoms, treatment methods and outcomes, pathological results, and follow-up results were retrospectively collected and analyzed.ResultsA total of 78 patients with 79 GISs were included, the female-to-male ratio was 55:23, and the average age was 52.12 ± 12.26 years. One-third (26/78) of the patients were asymptomatic. A total of 79 GISs were removed, and the average size was 3.63 ± 2.03 cm (range, 0.3–10 cm). As for tumor location, 54 GISs were located in the stomach, 14 in the esophagus, 2 in the duodenum, 6 in the colorectum (4 in the colon and 2 in the rectum), and the other 3 in the small intestine. A total of 23 and 55 patients underwent endoscopic and surgical resections, respectively. Compared with surgical resection, endoscopic resection is associated with a smaller diameter, lower cost, and shorter hospital stay. Pathological results revealed that S100 was positive in all the GISs. No recurrence was noticed during a median follow-up of 45 months (range, 6–148 months).ConclusionGISs are rare gastrointestinal tumors with favorable prognoses, which are most commonly seen in the stomach and diagnosed by pathological findings with immunohistochemical staining. Surgical resection remains the standard method for removing GISs, while endoscopic resection may serve as an alternative method for selected patients with GISs and may be attempted in GISs with a diameter of <3 cm and no signs of malignancy

Comparative Genomics Unravels the Functional Roles of Co-occurring Acidophilic Bacteria in Bioleaching Heaps

The spatial-temporal distribution of populations in various econiches is thought to be potentially related to individual differences in the utilization of nutrients or other resources, but their functional roles in the microbial communities remain elusive. We compared differentiation in gene repertoire and metabolic profiles, with a focus on the potential functional traits of three commonly recognized members (Acidithiobacillus caldus, Leptospirillum ferriphilum, and Sulfobacillus thermosulfidooxidans) in bioleaching heaps. Comparative genomics revealed that intra-species divergence might be driven by horizontal gene transfer. These co-occurring bacteria shared a few homologous genes, which significantly suggested the genomic differences between these organisms. Notably, relatively more genes assigned to the Clusters of Orthologous Groups category [G] (carbohydrate transport and metabolism) were identified in Sulfobacillus thermosulfidooxidans compared to the two other species, which probably indicated their mixotrophic capabilities that assimilate both organic and inorganic forms of carbon. Further inspection revealed distinctive metabolic capabilities involving carbon assimilation, nitrogen uptake, and iron-sulfur cycling, providing robust evidence for functional differences with respect to nutrient utilization. Therefore, we proposed that the mutual compensation of functionalities among these co-occurring organisms might provide a selective advantage for efficiently utilizing the limited resources in their habitats. Furthermore, it might be favorable to chemoautotrophs' lifestyles to form mutualistic interactions with these heterotrophic and/or mixotrophic acidophiles, whereby the latter could degrade organic compounds to effectively detoxify the environments. Collectively, the findings shed light on the genetic traits and potential metabolic activities of these organisms, and enable us to make some inferences about genomic and functional differences that might allow them to co-exist

GJB2 mutation spectrum in 2063 Chinese patients with nonsyndromic hearing impairment

Background: Mutations in GJB2 are the most common molecular defects responsible for autosomal recessive nonsyndromic hearing impairment (NSHI). The mutation spectra of this gene vary among different ethnic groups. Methods: In order to understand the spectrum and frequency of GJB2 mutations in the Chinese population, the coding region of the GJB2 gene from 2063 unrelated patients with NSHI was PCR amplified and sequenced. Results: A total of 23 pathogenic mutations were identified. Among them, five (p.W3X, c.99delT, c.155_c.158delTCTG, c.512_c.513insAACG, and p.Y152X) are novel. Three hundred and seven patients carry two confirmed pathogenic mutations, including 178 homozygotes and 129 compound heterozygotes. One hundred twenty five patients carry only one mutant allele. Thus, GJB2 mutations account for 17.9% of the mutant alleles in 2063 NSHI patients. Overall, 92.6% (684/739) of the pathogenic mutations are frame-shift truncation or nonsense mutations. The four prevalent mutations; c.235delC, c.299_c.300delAT, c.176_c.191del16, and c.35delG, account for 88.0% of all mutantalleles identified. The frequency of GJB2 mutations (alleles) varies from 4% to 30.4% among different regions of China. It also varies among different sub-ethnic groups. Conclusion: In some regions of China, testing of the three most common mutations can identify at least one GJB2 mutant allele in all patients. In other regions such as Tibet, the three most common mutations account for only 16% the GJB2 mutant alleles. Thus, in this region, sequencing of GJB2 would be recommended. In addition, the etiology of more than 80% of the mutant alleles for NSHI in China remains to be identified. Analysis of other NSHI related genes will be necessary

High-Dimensional Mahalanobis Distances of Complex Random Vectors

In this paper, we investigate the asymptotic distributions of two types of Mahalanobis distance (MD): leave-one-out MD and classical MD with both Gaussian- and non-Gaussian-distributed complex random vectors, when the sample size n and the dimension of variables p increase under a fixed ratio c=p/n→∞. We investigate the distributional properties of complex MD when the random samples are independent, but not necessarily identically distributed. Some results regarding the F-matrix F=S−12S1—the product of a sample covariance matrix S1 (from the independent variable array (be(Zi)1×n) with the inverse of another covariance matrix S2 (from the independent variable array (Zj≠i)p×n)—are used to develop the asymptotic distributions of MDs. We generalize the F-matrix results so that the independence between the two components S1 and S2 of the F-matrix is not required

Electromagnetic Performance Prediction for the Symmetrical Dual Three-phase Surface-mounted PMSM under Open-phase Faults Based on Accurate Subdomain Model

The paper presents an accurate analytical subdomain model for predicting the electromagnetic performance in the symmetrical dual three-phase surface-mounted permanent magnet synchronous machine (PMSM) under open-phase faulty conditions. The model derivations are extended from previous accurate subdomain models accounting for slotting effects. Compared with most conventional subdomain models for traditional three-phase machines with nonoverlapping winding arrangement, the subdomain model proposed in this paper applied for the 24-slot/4-pole dual three-phase machine with symmetrical overlapping winding arrangement. In order to investigate the postfault electromagnetic performance, the reconfigured phase currents and then current density distribution in stator slots under different open-circuit conditions are discussed. According to the developed model and postfault current density distribution, the steady-state electromagnetic performance, such as the electromagnetic torque and unbalanced magnetic force, under open-circuit faulty conditions are obtained. For validation purposes, finite element analysis (FEA) is employed to validate the analytical results. The result indicate that the postfault electromagnet performance can be accurately predicted by the proposed subdomain model, which is in good agreement with FEA results

Design of the fuzzy PI control system for load voltage in hybrid distribution transformer

Hybrid distribution transformer (HDT) is a novel transformer that has a powerful control on grid current and load voltage, and it is significant for the construction of the smart grid. The load voltage control is the key part in HDT control system. Here, a load voltage control strategy based on fuzzy PI controller is proposed, since the traditional PI controller cannot achieve satisfying dynamic performance under the operation of grid voltage change. The fuzzy controller can respond faster than PI controller for the outputs that is only determined by inputs and independent with time, when the grid voltage rags or swells. While combining the fuzzy controller with the PI controller, the fuzzy control will cover the shortage of PI control in transient process and the PI control ensures that the static performance will not be affected. In the end, the simulation model of HDT is carried out, and the result shows that the load voltage can track the reference faster than the traditional PI controller, which improves the performance of voltage control system